Inside-Out versus Outside-In models for virus induced demyelination: axonal damage triggering demyelination
نویسندگان
چکیده
منابع مشابه
A Mechanism of Virus-Induced Demyelination
Myelin forms an insulating sheath surrounding axons in the central and peripheral nervous systems and is essential for rapid propagation of neuronal action potentials. Demyelination is an acquired disorder in which normally formed myelin degenerates, exposing axons to the extracellular environment. The result is dysfunction of normal neuron-to-neuron communication and in many cases, varying deg...
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ژورنال
عنوان ژورنال: Springer Seminars in Immunopathology
سال: 2002
ISSN: 0344-4325,1432-2196
DOI: 10.1007/s00281-002-0105-z